iS Clinical
Pro-Heal Serum Advance+
Some links on this page are affiliate links. We may earn a small commission if you make a purchase — at no extra cost to you. This does not influence our ratings or reviews.
Professional-grade vitamin C + retinol + GHK-Cu combination serum; one of the few products deliberately combining these three actives with stabilisation chemistry to prevent copper-ascorbic acid destabilisation
Community Rating
Derm Mentions
47
Concentration
15% L-Ascorbic Acid; 0.5% Retinol; GHK-Cu concentration undisclosed
Peptides in this product
Other key ingredients
Pros
- ✓Combines three well-evidenced actives (vitamin C, retinol, GHK-Cu) in a single stable formula
- ✓Widely used and recommended in professional aesthetic practice and dermatology clinics
- ✓Research-grade formulation quality with evidence of photodamage, hyperpigmentation, and acne improvement
- ✓Suitable for sensitive skin including rosacea-prone skin due to the stabilised, low-irritant formula
Cons
- ✗High price per ml for a vitamin C-forward serum when compared to standalone L-ascorbic acid serums
- ✗GHK-Cu concentration is undisclosed — notable given that copper and ascorbic acid can interact
- ✗Retinol content means this is not appropriate for use during pregnancy
- ✗Requires gradual introduction for skin not accustomed to combined vitamin C and retinol actives
Best for skin type
all skin types; particularly beneficial for sensitive, blemish-prone, or post-procedure skin
Similar products
One of the highest disclosed concentrations of GHK-Cu available in a retail product; formulated specifically around copper peptide stability and bioavailability
Budget scalp peptide serum combining three researched hair-density complexes (Procapil, REDENSYL, AnaGain) with GHK-Cu; one of the most affordable hair peptide products available
Plant-based vegan hair serum combining phyto-actives and synthetic peptides; marketed for hair thinning reduction and density improvement with clinical data from brand-sponsored studies
Compare Products
Side-by-side product comparison
Take the Peptide Quiz
Get personalized recommendations
Last verified: 2025-03-01
Medical Disclaimer
The information on this site is for educational and informational purposes only. It is not intended as medical advice and should not be used to diagnose, treat, or prevent any condition. Always consult with a qualified healthcare professional before starting any new supplement, peptide, or treatment protocol.