Drunk Elephant

Protini Polypeptide Cream

$68.0050ml($1.36/ml)Cream

Premium signal peptide moisturiser beloved by dermatologists for its clean formulation and results in mature and sensitive skin

Community Rating

4.5/ 5.0

Derm Mentions

61

Concentration

undisclosed

Peptides in this product

Other key ingredients

Signal Peptides blend (Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-7)Pygmy Waterlily Stem Cell ExtractAmino AcidsPygmy Waterlily Stem Cell ExtractCassia Isatidis Root ExtractFruit Enzymes (Pomelo, Watermelon)

Pros

  • Clean, fragrance-free, essential-oil-free formulation appropriate for sensitive and rosacea-prone skin
  • Strong social proof among dermatologists and skincare professionals
  • Rich but non-greasy texture that works well as a stand-alone moisturiser
  • Combines signal peptides with hydrating ingredients for a dual-action approach

Cons

  • Premium price — significantly more expensive per ml than comparable peptide creams
  • Individual peptide concentrations are not disclosed
  • Jar packaging exposes the full product to light and air degrading active stability over time
  • Fruit enzyme addition may cause sensitivity in a small subset of reactive skin types

Best for skin type

all skin types; especially normal to dry

Last verified: 2025-03-01

Medical Disclaimer

The information on this site is for educational and informational purposes only. It is not intended as medical advice and should not be used to diagnose, treat, or prevent any condition. Always consult with a qualified healthcare professional before starting any new supplement, peptide, or treatment protocol.