TB-500
FitnessAlso known as: Thymosin Beta-4, Tβ4
Limited EvidenceWhat is TB-500?
Tissue repair peptide popular in sports recovery communities. A synthetic fragment of Thymosin Beta-4, it is banned in competitive sports and has limited human clinical data.
How it works
Promotes cell migration and proliferation, supports blood vessel formation (angiogenesis), and reduces inflammation by upregulating actin-binding proteins involved in tissue repair.
What marketers claim
- ▸rapid injury recovery
- ▸muscle repair
- ▸significant performance enhancement
- ▸safe for all athletes
What evidence supports
- ✓animal studies show wound healing and tissue repair benefits
- ✓may reduce inflammation in preclinical models
- ✓very limited human clinical data available
Best for
Safety notes & concerns
Full safety guide →- ⚠not FDA approved
- ⚠banned by WADA — positive drug test risk for competitive athletes
- ⚠unregulated sourcing and purity concerns
- ⚠unknown long-term safety profile in humans
Pairs well with
Use caution with
Frequently asked questions
Is TB-500 banned in sports?
Yes. TB-500 (Thymosin Beta-4) is on the World Anti-Doping Agency (WADA) prohibited list. Competitive athletes who test positive face sanctions. It is not appropriate for anyone subject to drug testing.
What is the difference between TB-500 and Thymosin Beta-4?
TB-500 is a synthetic fragment of the naturally occurring protein Thymosin Beta-4. They share the same active region but are not identical. Most products sold as TB-500 contain the synthetic peptide fragment.
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Last updated: 2025-03-01
Medical Disclaimer
The information on this site is for educational and informational purposes only. It is not intended as medical advice and should not be used to diagnose, treat, or prevent any condition. Always consult with a qualified healthcare professional before starting any new supplement, peptide, or treatment protocol.