TB-500
FitnessAlso known as: Thymosin Beta-4, Tβ4
Limited EvidenceWhat is TB-500?
Tissue repair peptide popular in sports recovery communities. A synthetic fragment of Thymosin Beta-4, it is banned in competitive sports and has limited human clinical data.
How it works
Promotes cell migration and proliferation, supports blood vessel formation (angiogenesis), and reduces inflammation by upregulating actin-binding proteins involved in tissue repair.
What marketers claim
- ▸rapid injury recovery
- ▸muscle repair
- ▸significant performance enhancement
- ▸safe for all athletes
What evidence supports
- ✓animal studies show wound healing and tissue repair benefits
- ✓may reduce inflammation in preclinical models
- ✓very limited human clinical data available
Best for
experimental recovery protocols under medical supervision
Safety notes & concerns
- ⚠not FDA approved
- ⚠banned by WADA — positive drug test risk for competitive athletes
- ⚠unregulated sourcing and purity concerns
- ⚠unknown long-term safety profile in humans
Pairs well with
BPC-157 (commonly stacked in biohacking protocols)
Use caution with
consult physician before usenot appropriate during pregnancy or with a history of cancer
Last updated: 2025-03-01
Medical Disclaimer
The information on this site is for educational and informational purposes only. It is not intended as medical advice and should not be used to diagnose, treat, or prevent any condition. Always consult with a qualified healthcare professional before starting any new supplement, peptide, or treatment protocol.