CJC-1295

Fitness

Also known as: CJC-1295 DAC, Modified GRF 1-29, Mod GRF

Limited Evidence

What is CJC-1295?

A growth hormone releasing hormone (GHRH) analog popular in anti-aging and bodybuilding communities. Often combined with Ipamorelin. Not FDA approved and sold through gray-market peptide suppliers.

How it works

Mimics natural growth hormone releasing hormone (GHRH) to stimulate the pituitary gland to produce and release more growth hormone. The DAC (Drug Affinity Complex) variant extends its half-life from minutes to days, creating a sustained GH elevation.

What marketers claim

▸dramatically increases muscle mass
▸burns fat rapidly
▸reverses aging
▸safe alternative to HGH injections

What evidence supports

✓demonstrated ability to increase growth hormone secretion in clinical studies
✓phase II trials showed sustained IGF-1 elevation
✓development was discontinued by the pharmaceutical company — not due to safety but commercial reasons

Best for

those exploring growth hormone optimization under medical supervision

Safety notes & concerns

⚠not FDA approved for any indication
⚠long-term safety data in humans is very limited
⚠unregulated supply chain — purity and dosing unreliable
⚠may cause water retention, tingling, and flushing
⚠potential risk of stimulating growth of existing tumors via IGF-1 elevation
⚠injection-based — carries infection risk without medical supervision

Pairs well with

Ipamorelin (commonly combined as CJC/Ipamorelin stack)

Use caution with

history of cancer or active tumorsconsult physician before usenot appropriate during pregnancy

Last updated: 2025-03-21

Medical Disclaimer

The information on this site is for educational and informational purposes only. It is not intended as medical advice and should not be used to diagnose, treat, or prevent any condition. Always consult with a qualified healthcare professional before starting any new supplement, peptide, or treatment protocol.